Enhancement of magnetization transfer effects by inter-molecular multiple quantum filtered NMR

Uzi Eliav^a and Gil Navon^{, a,
a}School of Chemistry, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel
Received 10 May 2007. Available online 28 September 2007.

Abstract

There are a number of methods that give MRI contrasts based on changes of the water M_z magnetization as a result of magnetization transfer to macromolecules. In the present work we report that a combination of these methods with inter-molecular multiple quantum coherences (iMQC) gives enhanced effects. For the magnetization transfer contrast (MTC) method an effect of (M_z/M₀) becomes (M_z/M₀)^l where l is the rank of the tensors constituting the iMQC. A similar trend was found upon combining iMQC with the Goldman–Shen experiment. It is pointed out that the method is general for all magnetization transfer methods, including the nuclear Overhauser effect.

Keywords: iMQC; Intermolecular dipolar interaction; Magnetization transfer; MTC; Goldman–Shen