Magnetic resonance microscopic imaging based on high-order intermolecular multiple-quantum coherences

Jee-Hyun Cho, Sangdoo Ahn, Chulhyun Lee, Kwan Soo Hong, Kee-Choo Chung, Suk-Kyu Chang, Chaejoon Cheong and Warren S. Warren
Magnetic Resonance Imaging
Article in Press, Corrected Proof

Abstract

Most imaging studies using intermolecular multiple-quantum coherences (iMQCs) have focused on the two-spin dipolar interactions — zero and double quantum coherences. Here, we report the results of various experimental studies to assess the feasibility of magnetic resonance microscopy with high-order iMQCs in model systems at 7 and 14 T. Experimental results demonstrated that the iMQC microscopic images with high coherence orders are readily observable at high field and have unique contrast depending on the sample microstructure and coherence order.

Keywords: Intermolecular multiple-quantum coherence; iTQC; iQQC; MR microscopy